Viagra could soon be used for heart disease patients: researchers.
6:00AM BST 20 Oct 2014.
A daily dose of Viagra could become a safe treatment for heart disease, researchers have said, after finding it improved blood flow.
The drug, normally used to treat erectile dysfunction, was found to prevent changes to the heart associated with disease.
Because it is already on the market and known to be safe, the researchers said there was no reason it could not be used immediately but said larger trials would be beneficial.
A team from Sapienza University of Rome analysed animal studies involving Viagra and conducted new research using 1,622 people with heart disease.
Lead author of the study, Andrea Isidori said: “We found that the main ingredient in Viagra can be used as an effective, safe treatment for several patients with heart disease. Large clinical trials are now urgently needed to build on these encouraging findings.”
Related Articles.
The results were published in the journal BioMed Central Medicine.
Phosphodiesterase-5 inhibitor (PDE5i) is the main ingredient in Viagra and other drugs commonly used to treat erectile dysfunction. The inhibitor blocks the enzyme PDE5, which prevents relaxation of smooth muscle tissue.
The analysis shows that PDE5i prevented the heart increasing in size and changing shape in patients suffering from left ventricular hypertrophy, a condition which causes thickening of the muscles in the left ventricle.
It also improved heart performance in all patients with different heart conditions without dangerous side effects such as raising blood pressure.
The study concludes that the inhibitor could be reasonably administered to men who suffer from heart muscle thickening and early-stage heart failure, a condition where the heart fails to beat with sufficient force.
Maureen Talbot, Senior Cardiac Nurse at the British Heart Foundation, said: “Often in medicine, drugs which are used to treat one ailment can have side effects that make it an effective treatment for other conditions.
“Viagra is already a prime example of this. But this study suggests it has the potential to be put to another use – treating early stage heart failure and cardiac hypertrophy.
“But we shouldn’t get too excited too quickly. Large randomised controlled trials are needed on both men and women to support this study’s findings before it could be recommended to heart patients.”
Health News.
Rebecca Smith »
Weird X-rays.
Life begins at 70.
Living proof: the secret of healthy ageing.
Why olive oil should be kept out of the frying pan.
Ebola outbreak in pictures.
Top news galleries.
Woody Allen’s 30 best one-liners.
Martin Chilton selects 30 great one-liners from the comedian and film star Woody Allen.
The best British political insults.
A hilarious history of political insults and putdowns, from Churchill to Corbyn.
Culture stars who died in 2016.
We celebrate and remember the culture stars who have passed away in 2016.
US Presidents: 30 great one-liners.
Great quotes from White House incumbents: will Donald Trump be joining them?
100 funny jokes by 100 comedians.
One hundred whip-smart wisecracks.
History’s greatest conspiracy theories.
From global warming to 9/11, Shakespeare to Elvis, Diana to JFK, peak oil to Roswell, conspiracy theories abound.
Grand stand views of London.
In pics: Stunning aerial shots of London’s football stadia by photographer Jason Hawkes.
Russia’s abandoned space shuttles.
In pics: The crumbling remains of the Soviet Union’s space programme.
Home-made in China.
Ambitious Chinese inventors take on crazy do-it-yourself projects.
Sinkholes around the world.
In pics: Sinkholes, craters and collapsed roads around the world.
Large rat climbs on sleeping commuter.
Teen pepper-sprayed at Trump rally.
Disabled great-grandfather denied stairlift and forced to crawl.
Elderly wombat rescued after being attacked.
EgyptAir crew finally arrive in Cairo.
When media meets medicine.
More from The Telegraph.
More from the web.
More from The Telegraph.
The latest news, opinion and analysis.
Catch up on all the latest football news and results.
All the latest film trailers, reviews and features.
Enter one of our exciting new competitions.
© Copyright of Telegraph Media Group Limited 2017.