flibanserin.
Omudhome Ogbru, PharmD.
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Charles Patrick Davis, MD, PhD.
Dr. Charles “Pat” Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.
What is flibanserin, and how does it work (mechanism of action)?
Addyi (flibanserin) is an oral drug used for treating low sexual desire in women. The mechanism of action of flibanserin is not completely understood. Flibanserin affects the way the brain works by interfering with communication among the brain’s nerves in areas of the brain that control sexual desire and other pleasurable sensations. Nerves communicate with each other by making and releasing chemicals called neurotransmitters. The neurotransmitters travel to other nearby nerves where they attach to receptors on nerves. The attachment of neurotransmitters either stimulates or inhibits the function of the nearby nerves. Flibanserin blocks several of the receptors on nerves including dopamine type 4, and serotonin type 2A, 2B and 2C receptors. It also stimulates serotonin type 1A. How these effects improve sexual desire in women is unknown. Scientists think that flibanserin may regulate areas of the brain that control sexual desire in premenopausal women with reduced sexual interest and desire. The FDA approved flibanserin on August 18, 2015.
What brand names are available for flibanserin?
Is flibanserin available as a generic drug?
GENERIC AVAILABLE: No.
Do I need a prescription for flibanserin?
What are the side effects of flibanserin?
Flibanserin may cause low blood pressure and fainting. Patients should lie down and seek medical help if they experience fainting.
Flibanserin causes drowsiness and reduces alertness. Patients should avoid operating machinery, driving, or performing other dangerous activities for at least 6 hours after taking each dose of flibanserin.
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What is the dosage for flibanserin?
Flibanserin is administered once daily by mouth at bedtime. It should be stopped after 8 weeks if there is no improvement in symptoms.
Which drugs or supplements interact with flibanserin?
Flibanserin can cause low blood pressure and fainting. Therefore, flibanserin should not be combined with alcohol and other drugs that also cause low blood pressure.
Flibanserin is metabolized or broken down by liver enzymes. Drugs that induce the activity of these enzymes will decrease blood levels of flibanserin. Examples of such drugs include.
Flibanserin should not be combined with drugs that decrease its blood levels.
Drugs that block the action of enzymes that breakdown flibanserin will increase blood levels and side effects of flibanserin. Therefore, flibanserin should not be combined with.
Flibanserin increases blood levels of digoxin (Lanoxin). This may lead to digoxin toxicity.
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Is flibanserin safe to take if I’m pregnant or breastfeeding?
Flibanserin has not been adequately studied in pregnant women.
Flibanserin has not been studied in women who are breastfeeding. It is not known whether flibanserin is present in human milk.
What else should I know about flibanserin?
What preparations of flibanserin are available?
How should I keep flibanserin stored?
Flibanserin should be stored at room temperature between 15 C and 30 C (59 F and 86 F).
Flibanserin (Addyi) is a drug prescribed premenopausal women with acquired generalized hypoactive sexual desire disorder (HSDD) and are experiencing low sexual desire, marked distress, or interpersonal difficulty. Side effects, drug interactions, dosage, storage, and pregnancy and breastfeeding information should be reviewed prior to taking this medication.
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Diagnosis is made by taking a patient history and, at times, blood tests. Treatment options include hormone therapy, bioidentical hormone therapy, and medications. There are non-FDA approved natural home remedies such as:
Hot flashes also can be caused by other conditions. Scientific studies to prove the safety and effectiveness of these products in relieving hot flashes have not been adequately performed. Consult your health-care professional before taking any herbal supplement.
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Night sweats are severe hot flashes that occur at night and result in a drenching sweat. The causes of night sweats in most people are not serious, like menopause in women, sleep apnea, medications, alcohol withdrawal, and thyroid problems. However, more serious diseases like cancer and HIV also can cause night sweats. Your doctor will treat your night sweats depending upon the cause.
You may experience other signs and symptoms that are associated with night sweats, which depend upon the cause, but may include, shaking, and chills with a fever caused by an infection like the flu or pneumonia; unexplained weight loss due to lymphoma; women in perimenopause or menopause may also have vaginal dryness, mood swings, and hot flashes during the day; and low blood sugar in people with diabetes.
Other causes of night sweats include medications like NSAIDs (aspirin, acetaminophen, ibuprofen (Motrin, Advil), and naproxen (Aleve, Naprosyn), antidepressants, sildenafil (Viagra), and abuse of prescription or illegal drugs and drug withdrawal; hormone disorders like pheochromocytoma and carcinoid syndrome; idiopathic hyperhidrosis; infections like endocarditis, AIDs, and abscesses; alcoholism and alcohol withdrawal; drug abuse, addiction, and withdrawal; and stroke.
A doctor or other health care professional can treat your night sweats after the cause has been diagnosed.
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Female Viagra Addyi Side Effects
