Kamagra Gold 100mg/50mg Tablet Sildenafil Review: How Long Does it Last VS Kamagra, Viagra, and Cialis?

Kamagra Gold 100 mg is one of the famed “generic Viagra” products for impotence marketed online and domestically. This product is from one of India’s renowned pharmaceutical companies roster, Ajanta Pharma. Kamagra contains the active ingredient Sildenafil Citrate, which is efficacious in the management of impotence in patients. The PDE5 (phosphodiesterase type-5) inhibitor drugs such as Sildenafil Citrate (Viagra), Vardenafil (Levitra) and Tadalafil (Cialis) [1] have a number of other applications apart from its use for erectile dysfunction. These active pharmaceutical ingredients are also utilized in the management other clinical conditions, as the PDE5 inhibitors are also discovered to exert their effects on various body parts (“PDE5 inhibitors and their applications” by Giovannoni et al in 2010) [2].

The competition between generic Viagra products vs Kamagra in the impotence market heightened due to the increased presence of these products not only locally, but also on the internet market; plus, their prices are also increasingly competitive too. The manufacturer of Kamagra, Ajanta Pharma, made sure that its products are noticed by making the Kamagra product line highly competitive and inclusive of a lot of product formulations. Although Kamagra Gold is in the archetypal hard tablet form, Ajanta made oral jelly forms, chewable tablet forms, soft gel capsule forms, and dissolvable tablets for its Kamagra product line, which provides buyers ample choices for Sildenafil products.

Facts about Ajanta Pharma

The Indian pharmaceutical industry is eminent for its generic product manufacturing. One of the contributors to India’s vast production of medical products is the company Ajanta Pharma, which has an annual capacity of 1,740 Million tablets, 216 Million capsules and 150 Million powder formulations (sachets) in one facility alone [3]. As per Ajanta Pharma information, it has 6 production plants; 5 are domestically located in India, and the other facility is situated in Africa [3].

Ajanta Pharma Laboratory

Ajanta Pharma is no ordinary company since it has acquired accreditations not only from WHO (Good Manufacturing Practices certification) but also from the esteemed US FDA and United Kingdom’s MHRA [3,4]. Besides that, Ajanta Pharma’s products in several therapeutic areas are also US FDA-certified due to their quality and effectiveness [5].

Although the business is recognized for its production of impotence products, Ajanta Pharma is also able to conjure products for various therapeutic segments [4]. The enterprise is known for its capacity to tailor its products to the markets which it exists in, so in every country, Ajanta determines specific products which could benefit the nation’s market needs [4]. Ajanta has come a long way since its inauguration in 1973; it has now extended its influence in 30 countries [4] and plans on expanding its reach to more countries in the near future.

Sildenafil in Scientific Publications

It is initially believed that impotence in diabetic patients can also be managed by lifestyle modification practices and glycemic control. The study of Kirilmaz et al in 2015, “The effect of lifestyle modification and glycemic control on the efficiency of sildenafil citrate in patients with erectile dysfunction due to type-2 diabetes mellitus” is one of the papers tackling the effectiveness of lifestyle modification on the efficacy of Sildenafil for impotence in diabetes-induced ED [6]. 83 impotence patients were enrolled in the study and were sectioned into two groups; the first received lifestyle modification instructions for proper diet and exercise and glycemic control treatments (41 patients), while the second group received the same treatment, but with an additional Sildenafil Citrate dose (100 mg 2-3x per week) [6]. Following the results of the study (IIEF/International Index of Erectile Function Scores), there was a significant increase in the erectile functioning of patients administered with Sildenafil in addition to the lifestyle changes [6]. Kirilmaz et al, in the culmination of their study, deduced that merely implementing lifestyle changes and glycemic medications are insufficient for improving lost erectile function in diabetic patients with ED [6]. The authors reckoned that Sildenafil, too, should be administered to regain the lost erectile function for these diabetic ED patients [6].

According to Sousa et al, the consequence of Sildenafil Citrate use in human sperm behavior “remains controversial” (“Concentration-dependent Sildenafil citrate (Viagra) effects on ROS production, energy status, and human sperm function” in 2014) [7]. The authors, in their paper, evaluated whether mitochondrial dysfunction (membrane potential, reactive oxygen species production, and changes in energy content) are due to Sildenafil Citrate’s effect on sperm function [7]. Sousa et al determined that Sildenafil caused decreased sperm motility and it’s due to the drug’s effect on the mitochondria (cell powerhouse) and ATP/adenosine triphosphate production (sperm mitochondrial ATP levels decreased upon sperm exposure to Sildenafil) [7]. Although there is a marked decrease in the sperm function with the cells’ exposure to Sildenafil, the authors resolved that there may still be other factors influencing this ATP-mitochondrial/sperm motility decline observed in the study [7].

The study “Dose-dependent protective effect of sildenafil citrate on testicular injury after torsion/detorsion in rats” by Yıldız et al in 2012, on the other hand, investigated the outcome of Sildenafil use in rats with testicular injury caused by testicular torsion/detorsion (T/D) [8]. Yıldız discovered that the low-dose of Sildenafil administration can lower testicular tissue damage parameters [8]. Owing to the result data outcome, the administration of low-dose Sildenafil prevents ischemia in the testicular torsion observed in the rat model [8].

Sildenafil Mode of Action

Sildenafil Citrate stimulates the initiation of the vasodilation and the endothelial smooth muscle relaxation in the penile tissues. This effect is accomplished by Sildenafil’s nature as a PDE5 inhibitor. As a PDE5 inhibitor, Sildenafil suppresses the action of the PDE5 enzyme in degenerating the cyclic monophosphate responsible in instigating the stimulation of the essential vasodilation and the endothelial smooth muscle relaxation in the penile tissues.

As Sildenafil suppresses the action of the PDE5, it encourages the increase of the presence of the cyclic monophosphate, which is responsible for commencing of the erectile response, even in patients with impotence. The Sildenafil Content of Kamagra usually lasts in an average of 4 hours, although there are studies mentioning that Sildenafil/Viagra actually lasts more than 4 hours.

Kamagra Gold Effects on Erectile Dysfunction

As a PDE5 inhibitor, Kamagra Gold is able to instigate an erectile response appropriate to the present sexual stimuli in patients with the impotence problem. Regardless of the cause of the dysfunction, Kamagra Gold’s Sildenafil Citrate API is able to initiate the erectile function, which helps the patients perform their sexual duties.

Although there are many applications possible for Sildenafil Citrate, the product Kamagra Gold and other generic Viagra products are specifically indicated for erectile dysfunction, and their doses are not optimized for other applications other than for impotence. The patients can enjoy 4-8 hours of restored erectile function with the use of Kamagra Gold.

Length of Therapy and Recommended Doses

There is no difference in the initially indicated dose for Viagra/generic Viagra products vs Kamagra. The same 50 mg to 100 mg dose is indicated initially by doctors for Kamagra. Kamagra Gold is advised to be taken with lots of water (but not alcohol), 30 minutes to 4 hours before the coital activity.

No current recommendations regarding how long the product should be consumed by patients with impotence. Some studies mention that dropouts in long-term Sildenafil studies are caused by the restoration of erectile function in patients. But, the results are still conflicting with the long-term therapy with Sildenafil for impotence, as there are patients who still require the perpetual administration of Sildenafil for their erectile function.

Adverse Effects and Alerts

PDE5 inhibitor drugs such as Sildenafil (Viagra), Tadalafil (Cialis), and Vardenafil (Levitra), are with inevitable side effects for some of the treated patient population. Generic Viagra products vs Kamagra also exhibit side effects in patients using the treatments. Headaches, heartburn, vision changes, dyspepsia, and facial flushing rank as the most commonly exhibited side effects in patients [9]. These adverse effects, although bothersome, are able to fade away with the continuous therapy with Sildenafil Citrate, as the drug is properly flushed out of the body.

Contraindications

Notorious interactions ascertained for Sildenafil Citrate (thus for Kamagra too) are with Nitrate medications (of all forms), antiretroviral medications for HIV/AIDS/Hepatitis, antifungal products (systemic and topical), antibacterial products, antibiotics, and some herbal remedies, supplements (vitamins and minerals), and even grapefruit juice and St. John’s wort. These products should be avoided when prescribed with Sildenafil, and for safety, patients should let their doctors know all the medications they are taking so the doctors can resolve which ones are safe to take and which drugs are precarious for their condition.

Customer Reviews

Because Kamagra Gold by Ajanta is popular online, it has several client feedbacks available on the web:

Kamagra Gold Feedback

One online web store has several user reviews for Kamagra Gold. L Thompson, one of the buyers from the shop, conferred Kamagra Gold with 5 stars and said that Kamagra indeed is efficacious and based on his words, the drug gave him the “expected results”.

Kamagra Gold Testimonial

In another online shop selling Kamagra Gold 100 mg, one consumer also aired his thoughts on the drug he’s recently bought. Guinnavere even cited that Kamagra works rather well, “just as Viagra does”. The reference to the branded impotence product is high praise for Kamagra, considering their price differs by miles. It is interesting, too, that Guinnavere mentioned that when in a rush, his boyfriend dissolves the product under his tongue for faster absorption, although Kamagra Gold is not really a sublingual or a chewable tablet.

Kamagra Gold Customer Experience

Another buyer, Alfie, gave Kamagra Gold an excellent rating and stated that the product was “well worth the money”. Alfie even cited that Kamagra also “lasted quite long” based on his use. Although Alfie did not expound more on the effectiveness of Kamagra, he was clearly a satisfied client due to his 5-star rating for the generic Viagra impotence product.

Kamagra Price, Forms, and Existing Dosage

Albeit Ajanta Pharma manufactures various forms for its Kamagra products, its Kamagra Gold product is only marketed in the mainstream tablet form and in 100 mg only. Stores online sell Kamagra gold and the images below illustrate an example of Kamagra Gold’s Internet price:

Kamagra Gold Prices

Kamagra Gold is a good, cheap option for Viagra users as one pill costs $1.53 (the maximum) in one online store. The store says that it gives freebie pills, but when you compute the cost, there’s actually no freebie for the product, which is rather misleading.

Kamagra Gold in Shopping Cart

Shipping for Kamagra Gold varies from one store to another. Vgraustralia.com charges $10-$30 for domestic and international shipping. The cost is actually reliant on which courier are the buyers willing to use for their orders.

Kamagra Gold Shipping Cost

Another online pharmacy, Alldaychemist.com, charges a fixed rate of $25 for every purchase but has a promotional offer for subsidized shipping costs when buyers purchase via the preferred payment options. The postage rates are the same regardless of location. USA, Australia, and Canada buyers pay for the same shipping rate, as per store policy.

Conclusion and Rating

Kamagra Gold 100 mg is another successful generic Viagra product by Ajanta Pharma. The reviews available for the product are positive about the drug’s efficacy, and there seldom are complaints about Kamagra Gold online. In the client preference fight between other generic Viagra brands vs Kamagra, though, we can’t really tell which brand has the upper hand, as there are still other famous generic names which are popular with users too. However, we can still give Kamagra 4 out of 5 due to its good reception by the buyers and also its budget-friendly price.

Reference List

2. Giovannoni MP, Vergelli C, Graziano A, Dal Piaz V. PDE5 inhibitors and their applications. Current medicinal chemistry. 2010 Aug 1; 17(24):2564-87. Accessible from: https://www.ncbi.nlm.nih.gov/pubmed/20491634

6. Kirilmaz U, Guzel O, Aslan Y, Balci M, Tuncel A, Atan A. The effect of lifestyle modification and glycemic control on the efficiency of sildenafil citrate in patients with erectile dysfunction due to type-2 diabetes mellitus. The Aging Male. 2015 Oct 2; 18(4):244-8. Accessible from: https://www.ncbi.nlm.nih.gov/pubmed/26248034

7. Sousa MI, Amaral S, Tavares RS, Paiva C, Ramalho-Santos J. Concentration-dependent Sildenafil citrate (Viagra) effects on ROS production, energy status, and human sperm function. Systems biology in reproductive medicine. 2014 Apr 1; 60(2):72-9. Accessible from: https://www.ncbi.nlm.nih.gov/pubmed/24350988

8. Yıldız H, Durmus AS, Şimşek H, Yaman M. Dose‐dependent protective effect of sildenafil citrate on testicular injury after torsion/detorsion in rats. Andrologia. 2012 May 1; 44(s1):300-6. Accessible from: https://www.ncbi.nlm.nih.gov/pubmed/21749432

About Sam W. Johnson

Working in pharmacology for a long time, Sam gained knowledge and experience which he shares in his product reviews. His great skills of finding and analyzing information help him in writing short, solid and useful reviews.