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Month: May 2025

Posted by admin on May 29, 2025June 6, 2025

Tadalafil and Sildenafil: Enhancing Bladder Vascular Health through Nitrergic Nerve Mechanisms

Erectile dysfunction medications, notably phosphodiesterase-5 (PDE5) inhibitors such as tadalafil and sildenafil, have long enjoyed fame (and perhaps some infamy) for their effects beyond mere sexual enhancement. Interestingly, recent scientific investigations suggest these drugs could significantly benefit individuals suffering from…

Posted by admin on May 27, 2025June 6, 2025

Sildenafil and DRESS Syndrome: A Rare Yet Serious Reaction

When one thinks of sildenafil, more commonly known under its brand name Viagra®, the typical side effects that come to mind are usually mild headaches, flushing, or perhaps a stuffy nose. However, medicine, with its delightful unpredictability, sometimes presents rare…

Posted by admin on May 23, 2025May 27, 2025

Uvaria Chamae and Cylicodiscus Gabunensis: Promising Natural Alternatives to Sildenafil for Erectile Dysfunction Treatment

Erectile dysfunction (ED) remains one of the most prevalent male health concerns worldwide, affecting men across various age groups. While conventional medications like sildenafil citrate (Viagra) have proven highly effective, their potential side effects, cost, and the stigma associated with…

Posted by admin on May 15, 2025May 27, 2025

Immunomodulatory Effects of Sildenafil on Placental Immune Cells in Early-Onset Fetal Growth Restriction

Early-onset fetal growth restriction (eoFGR) is a significant pregnancy complication characterized by the fetus not achieving its inherent growth potential. It remains a major clinical challenge, carrying high risks of perinatal morbidity and mortality. Placental insufficiency, often resulting from impaired…

Posted by admin on May 13, 2025May 15, 2025

Understanding the Expiration and Safety of Viagra® and Cialis®

When it comes to medications, especially those for erectile dysfunction (ED) like Viagra® (sildenafil) and Cialis® (tadalafil), understanding expiration dates isn’t just a formality—it’s essential for your health and safety. While many might casually assume that medications simply lose their…

Posted by admin on May 12, 2025May 15, 2025

The Hidden Dangers of Sildenafil Overdose: Understanding Risks and Ensuring Safe Usage

The Rise of Sildenafil: Miracle Drug or Hidden Danger? Since its introduction to the market in 1998, Sildenafil—widely recognized under the brand name Viagra—has dramatically altered the therapeutic landscape for erectile dysfunction (ED). Originally developed to treat cardiovascular disorders, Sildenafil…

Posted by admin on May 10, 2025May 27, 2025

Unlocking the Mysteries of the External Urethral Sphincter: From Basic Physiology to Clinical Innovation

A Complex Muscle with Simple Yet Vital Roles Despite its fundamental role in maintaining urinary continence and facilitating normal voiding, the external urethral sphincter (EUS) has historically been overshadowed by research on other urinary tract structures, particularly the bladder. Comprising…

Posted by admin on May 8, 2025May 27, 2025

Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS): Current Clinical Status and Emerging Scientific Directions

Understanding IC/BPS: The Complexity Behind the Symptoms Interstitial cystitis/Bladder pain syndrome (IC/BPS) is a debilitating chronic condition characterized primarily by persistent pelvic pain and uncomfortable urinary symptoms. Despite extensive research, it remains a clinical enigma, difficult to diagnose and even…

Posted by admin on May 3, 2025May 27, 2025

The Sensory System in Overactive Bladder: New Frontiers in Pharmaceutical Therapy

Rethinking the Bladder as an Unreliable Witness “The bladder is an unreliable witness,” a statement often echoed by urologists, underscores the complexity of diagnosing urinary disorders based solely on patient-reported symptoms. Lower urinary tract symptoms (LUTS)—ranging from urgency and frequency…

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  • Testosterone, Nitric Oxide, and Human Erectile Physiology: Insights from Cavernosal Tissue Research
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  • Estrogen Metabolites, Oxidative Stress, and the Pathophysiology of Treatment-Resistant Depression
  • Sildenafil, Sleep Deprivation, and Male Sexual Reflexes: Untangling Hormonal and Neurophysiological Pathways
  • Sildenafil and Alzheimer’s Disease: Exploring the Promise of Drug Repurposing in Neurodegeneration
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  • Benign Prostatic Hyperplasia and Erectile Dysfunction: A Comprehensive Guide for the General Practitioner
  • Pharmacological Strategies for Antidepressant-Induced Sexual Dysfunction in Women: Evidence, Challenges, and Clinical Insights
  • Sildenafil Citrate-Based Hydrogels in Traumatic Wound Healing: Innovation, Efficacy, and Safety
  • Indonesian Medicinal Plants in the Management of Erectile Dysfunction: Scientific Insights and Future Prospects
  • Androgen-Deprivation Therapy, Leuprolide, and Sildenafil: Untangling the Metabolic and Cardiovascular Puzzle in Prostate Cancer
  • Sildenafil Citrate and the Protection of Contralateral Testis After Torsion-Detorsion: Mechanistic Insights and Clinical Relevance
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  • Advanced Hydrogels: A New Horizon in the Management of Organic Erectile Dysfunction
  • Pharmacological Pathways to Desire: Recent Advances in Treating Female Sexual Interest and Arousal Disorder
  • Non-Medical and Non-Invasive Approaches to Erectile Dysfunction in Men with Type 2 Diabetes: A Comprehensive Review
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  • Pharmacological Strategies for Ureteral Stent-Related Discomfort: Evidence, Mechanisms, and Clinical Perspectives
  • Female Sexual Dysfunction and Emerging Pharmacotherapies: The Roles of Flibanserin, Sildenafil, and Testosterone
  • Erectile Dysfunction and the Role of Pharmacy Technicians in Somalia: Knowledge, Attitudes, and Practices
  • Sildenafil Citrate in Secondary Pulmonary Hypertension: Short-Term Clinical Benefits and Mechanistic Insights
  • Nutritional Aphrodisiacs: Biochemistry, Pharmacology, and Clinical Perspectives
  • Erectile Dysfunction as a Harbinger of Myocardial Infarction
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